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What Comes Next Today's sessions are scheduled to begin at approximately 10:15 a.m

doi: 10.1016/j.neulet.2017.07.001 41 RaperJ.De BiasioJ

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SFAs are also thought to directly induce an inflammatory response in the brain by activating toll-like receptor (TLR) receptors in microglia, causing elevated cytokines IL-6, interleukin-1 (IL-1), and TNF-, particularly in the hippocampus, which has been shown to correlate with depressive behavior in mice (3234)

This activation then stimulates PPARs, nuclear respiratory factors 1 and 2 (Nrf1/2), and estrogen receptor-related receptors (ERR), enhancing the expression and activity of TFAM (Fontecha-Barriuso et al., 2020